Dragon SpX-18 (CRS-18 ), IDA-3, RFTSat - Falcon 9-074 (B1056.2) - CCAFS SLC-40 - 25.07.2019 22:01 UTC

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40 мышей и 20 или 30 живыми вниз

 https://www.issnationallab.org/press-releases/rodent-research-mission-on-iss-national-lab-enables-investigators-to-leverage-space-flown-specimens/

Rodent Research Mission on ISS National Lab Enables Investigators to Leverage Space-Flown Specimens
JULY 18, 2019



KENNEDY SPACE CENTER (FL), July 18, 2019 – Onboard SpaceX's 18th commercial resupply services mission contracted by NASA, the International Space Station (ISS) U.S. National Laboratory will send 40 female mice to the microgravity environment of the orbiting platform to evaluate their adaptation off Earth. Rodent spaceflight experiments provide a broad range of translational data pertinent to biomedical advancements in neurology, muscle and bone physiology, immunology, and cardiovascular and developmental biology. Due to the tremendous demand from the research community for leveraging model organisms, the ISS National Lab announced its second Rodent Research Reference Mission earlier this year—allowing researchers the ability to analyze rodents post-spaceflight in an effort to accelerate medical breakthroughs that can pave the way toward advancements in industrial biomedicine, improving patient care on Earth.


With this launch, 30 mice will be returned alive to Earth at the completion of the SpaceX Dragon spacecraft's stay on station (approximately 30 days), while the remaining 10 will remain on the orbiting laboratory for additional exposure to microgravity.

This Rodent Research Reference Mission will allow selected researchers to further analyze biological specimens toward better disease modeling or potentially accelerated development of therapeutics for terrestrial use. Below highlights principal investigators (PIs) selected from the second Rodent Research Reference Mission who will analyze space-flown biospecimens:


Single-Cell Profiling of Immune Factors Related to Circulating microRNAs
NASA Ames Research Center
PI:  Afshin Beheshti


Gastrointestinal Alterations of Combined Aging and Spaceflight 
Texas A&M University Health Science Center
PI:  Walter Cromer


Comprehensive Analysis of Musculoskeletal System Changes in Mice Exposed to Microgravity
University of Colorado, Boulder
PI:  Virginia Ferguson


Single-cell RNA sequencing to Reveal Changes to Bone and Immune Functions Resulting from Spaceflight
NASA Ames Research Center
PI:  Jonathan Galazka


Computational Microstructure-Inspired and Data-driven Model for Bone Degradation to Study the Progression of Osteoporosis
Iowa State
PI:  Azadeh Sheidaei


Effects Spaceflight and Aging on the Circulation and Musculoskeletal Systems of the Hindlimb 
Florida State University
PI:  Anand Narayanan


Examination of the Combined Effects of Spaceflight and Aging on Specialized Circulations
Texas A&M University Health Science Center
PI:  Pooneh Bagher


Effects of Spaceflight and Aging on the Circulation of the Head and Neck: Implications for SANS
Florida State University
PI:  Michael Delp


Microgravity Unloading Influence on Age-Related Extracellular Matrix Remodeling and Fibrosis 
University of Washington
PI:  Jennifer Davis


Aging and Microgravity Effects on Ovarian Estrogen Production
University of Kansas Medical Center
PI:  Lane Christenson


This RFP is in association with Taconic Biosciences (who will provide the rodents) and BioServe Space Technologies (who will administer the biospecimens).


To learn more about ISS National Lab–sponsored payloads on SpaceX's 18th commercial resupply services mission to the space station, visit our launch coverage page.

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Но разночтения....

https://www.nasa.gov/mission_pages/station/research/experiments/explorer/Investigation.html?#id=7992
 Rodent Research-17 (RR-17)

wo groups of 20 C57BL/6 female mice (20 younger and 20 older per group for a total of 40 mice) live aboard the ISS in specially designed rodent habitats for durations of approximately one and two months.
 
One group comprised of 10 younger and 10 older mice returns to Earth live after ~30 days in space. The second group of 20 mice, 10 younger and 10 older, remains on the ISS for approximately 60 days. In both cases, animals are euthanized humanely, and tissue samples are harvested for subsequent study and comparison with Earth-based control groups.
...

Первый американский биопринтер
 https://www.issnationallab.org/blog/the-first-american-space-based-bioprinter-is-launching-soon/
 https://www.issnationallab.org/press-releases/americas-first-automated-bioprinter-for-spaceflight-launching-to-iss-national-lab-on-spacex-crs-18/

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Прогноз погоды L-3 на 24 июля

L-3 Falcon-9 CRS-18 Forecast 24 Jul

Пусковой день (24.07) - ↓ 30 % GO
Резервный день (25.07) - ↓ 20 % GO

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https://www.nasa.gov/press-release/nasa-updates-broadcast-of-next-space-station-resupply-launch-prelaunch-activities

July 20, 2019
MEDIA ADVISORY M19-075

NASA Updates Broadcast of Next Space Station Resupply Launch, Prelaunch Activities


A SpaceX Dragon spacecraft launches May 4, 2019, on a Falcon 9 rocket fr om Space Launch Complex 40 at Cape Canaveral Air Force Station in Florida on a NASA-contracted mission to resupply the International Space Station.
Credits: NASA
NASA commercial cargo provider SpaceX now is targeting 6:24 p.m. EDT Wednesday, July 24, for the launch of its 18th resupply mission to the International Space Station. Live coverage will begin on NASA Television and the agency's website with prelaunch events Tuesday, July 23.








The company's Dragon spacecraft will deliver supplies and critical materials to directly support dozens of the more than 250 science and research investigations that will occur during Expeditions 60 and beyond. In addition to bringing research to station, the Dragon's unpressurized trunk is carrying the International Docking Adapter-3 (IDA-3), which, when installed on the space station, will provide the microgravity laboratory with two common ports that expand opportunities for visiting vehicles, including new spacecraft designed to carry humans for NASA's Commercial Crew Program.





Dragon will dock to the space station Friday, July 26, and be greeted by NASA astronauts Nick Hague, Christina Koch and Andrew Morgan. Using the station's robotic arm, Hague will grab, or grapple, Dragon with Koch providing backup. Morgan will assist by monitoring telemetry during Dragon's approach. After Dragon capture, mission control in Houston will send ground commands for the station's robotic arm to rotate and install it on the bottom of the station's Harmony module.


Full mission coverage is as follows (all times Eastern):





Tuesday, July 23

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• 9 a.m. – NASA Social, What's on Board science briefing fr om NASA's Kennedy Space Center in Florida. This briefing will highlight the following research:
• Pete Hasbrook, manager of NASA's International Space Station Program Science Office, will provide an overview of the research being conducted on the space station and how it benefits exploration and humanity.
  
• Ken Shields, chief operating officer of the International Space Station's U.S. National Laboratory, will discuss the lab's work in advancing science in space and developing partnerships that drive industrialization.
  
• Gene Boland, chief scientist at Techshot, Inc., and Ken Church, chief executive officer at nScrypt, will discuss the BioFabrication Facility, which is designed to print organ-like tissues in microgravity, a stepping stone in a long-term plan to manufacture whole human organs in space using refined biological 3D printing techniques.
  
• Charles Cockell, professor of astrobiology at the University of Edinburgh, will discuss Biorock, an investigation that will provide insight into the physical interactions of liquid, rocks and microorganisms under microgravity conditions to inform potential mining of materials in space and benefit long-duration spaceflight missions.
  
• Valentina Fossati from the New York Stem Foundation Research Institute and Andres Bratt-Leal from Aspen Neuroscience will discuss the Space Tango – Induced Stem Cells investigation, wh ere cells from patients with Parkinson's disease and Multiple Sclerosis will be cultured on the space station to examine the cell-to-cell interactions that occur in such neurodegenerative diseases and inform the development of new treatments.
  
• Rasha Hammamieh, principal investigator from the U.S. Army Center for Environmental Health Research, and Melissa Kacena, co-investigator at the Indiana University School of Medicine, will discuss the Cell Science-02 investigation. This study compares the ability of two different bone-inducing growth factors, one novel and one currently used in bone healing therapies, to stimulate growth, differentiation and related cellular functions of osteoblast in the microgravity environment.
  
• Jason August, manager of the International Space Station Mission Evaluation Room, will discuss IDA-3, wh ere Boeing's CST-100 Starliner and SpaceX's Crew Dragon spacecraft will dock in the near future when it transports astronauts to the station.
  

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Wednesday, July 24

[/li]
• 10 a.m. – Prelaunch news conference from Kennedy with representatives from the agency's International Space Station Program, SpaceX and the U.S. Air Force's 45th Space Wing.
  
• 6 p.m. – NASA TV launch coverage begins for the 6:24 p.m. launch.
  

Friday, July 26

[/li]
• 5:30 a.m. – Dragon rendezvous, grapple and attaching to the station. Capture is scheduled for approximately 7 a.m.
  
• 9 a.m. – Dragon installation to the nadir port of the Harmony module of the station
  

Dragon will remain at the space station until Aug. 20, when the spacecraft will return to Earth with research and return cargo.

-end-

Last Updated: July 21, 2019
Editor: Karen Northon

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Прогноз погоды L-2 на 24 июля

L-2 Falcon-9 CRS-18 Forecast 24 Jul

Пусковой день (24.07) -  = 30 % GO
Резервный день (25.07) - ↑ 30 % GO

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https://blogs.nasa.gov/spacex/2019/07/22/l-2-weather-forecast-for-wednesdays-crs-18-launch/

L-2 Weather Forecast for Wednesday's CRS-18 Launch

Danielle Sempsrott
Posted Jul 22, 2019 at 1:42 pm


A SpaceX Falcon 9 rocket lifts off from Space Launch Complex 40 at Cape Canaveral Air Force Station in Florida on April 2, 2018, carrying the SpaceX Dragon resupply spacecraft. Photo credit: NASA/Tony Gray, Tim Powers, Tim Terry

Meteorologists with the U.S. Air Force 45th Space Wing predict a 30% chance of favorable weather for SpaceX's 18th Commercial Resupply Services (CRS-18) mission to the International Space Station. Primary weather concerns are cumulus clouds and their associated anvil clouds, as well as lightning.

The Falcon 9 rocket is scheduled to lift off from Space Launch Complex 40 at Cape Canaveral Air Force Station in Florida at 6:24 p.m. EDT on Wednesday, July 24. The company's Dragon spacecraft will deliver a number of science investigations, supplies and equipment to the station, including the International Docking Adapter-3 – a new docking adapter that will enable future spacecraft built under NASA's Commercial Crew Program to autonomously attach to station.

Launch day will begin with a prelaunch news conference at 10 a.m. with representatives from the International Space Station Program Science Office, SpaceX and the U.S. Air Force 45th Space Wing. Watch live on NASA TV or the agency's website.

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https://spacewatch.global/2019/07/spaceflight-to-launch-multiple-spacecraft-from-international-space-station-via-cygnus/

Spaceflight to Launch Multiple Spacecraft fr om International Space Station via Cygnus


SEOPS Mission Patch

Spaceflight has announced that it is providing mission management and rideshare integration services on an upcoming launch from the International Space Station (ISS) and Northrop Grumman's Cygnus launch vehicle. Spaceflight bought the capacity through an arrangement with Hypergiant SEOPS for a variety of customer spacecraft, including: RFTSat from Northwest Nazarene University; selected for flight via NASA's CubeSat Launch Initiative; NARSSCube-2 from NARSS-Egypt developed by researchers from NARSS-Egypt for technology demonstration and environmental study; launch was coordinated by Smart Integrators and an undisclosed 6U Cubesat

In a unique arrangement, the spacecraft will be arriving at the ISS through an ISS Cargo Resupply Mission aboard via a SpaceX Falcon 9 Dragon capsule from Cape Canaveral Air Force Station in late July. Spaceflight has named the mission SEOPS-1, but it is also referred to as ISS SpX18/NG11, representing the launch vehicles meeting at the ISS (a SpaceX Falcon 9 Dragon and a Northop Grumman Antares Cygnus).

"We are always looking for creative and innovative ways to get our customers' spacecraft in orbit, and our partnership with Hypergiant SEOPS helps us deliver on this promise," said Curt Blake, CEO of Spaceflight. "The rideshare campaign is a low schedule risk option because of the regular cadence of ISS Cargo Resupply Missions and the maturity of the Dragon/Falcon 9 and Cygnus/Antares launch systems. We're looking forward to commissioning more of these types of missions in the future."

The Cygnus vehicle is already docked at the ISS, following its launch on April 17, 2019 and landing on April 19, 2019. During the weeks following the arrival of the Dragon capsule in late July which will carry the rideshare customers' spacecraft, the ISS crew will transfer the cargo from the Dragon to the ISS, wh ere they will place the SEOPS SlingShot Deployer with the installed satellites into the SlingShot hardware attached to the Cygnus hatch bulkhead. After the ISS side-hatch is closed and the space between the ISS and Cygnus spacecraft depressurized, the ISS robotic arm will unberth the Cygnus from the ISS. Cygnus will then manoeuvre itself to a higher orbit (450-500 km altitude, 51.6-degree inclination) to deploy the satellites and conduct more tests.

SEOPS brings a wealth of experience to the mission, with personnel who have been responsible for deploying more than 200 small satellites from the ISS and Cygnus spacecraft since 2012. The team was responsible for the development, construction, qualification, safety and integration of these satellites through the NASA Human Space Program, one of the most demanding government qualification programs for spaceflight. In February 2019, SEOPS successfully completed the deployment using the SlingShot deployer from NG-10 – Cygnus.

"Our focus is on improving the Earth-to-Space experience for all customers whether it's through our ability to use machine learning and AI to interpret complex data, or in improving the ability of our customers to get to space when they want, how they want," said Chad Brinkley, Chief Space Officer at Hypergiant. "Spaceflight has been an integral partner in continuing to provide the best-in-class experience for our customers."

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Полигон открыт для подготовки и проведения пуска миссии SpX CRS-18

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Опубликована

Airspace Closure Area

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Объявлена

Launch Hazard Area

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П-к НАСА

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1

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Ведущая

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2

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3

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Биопринтер

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3b

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Biorock

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Cell Science-02

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Space Tango – Induced Stem Cells

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IDA-3